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Download fileAcute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia
journal contribution
posted on 2020-04-02, 11:04 authored by Daniel Bailey, Thomas Withers, Vicky Goosey-TolfreyVicky Goosey-Tolfrey, David Dunstan, Christof LeichtChristof Leicht, Rachael Champion, Opie Charlett, Louise FerrandinoElevated levels of cardiovascular disease (CVD) risk markers are highly prevalent in people with a spinal cord injury (SCI). Breaking up prolonged sedentary time with short, regular bouts of physical activity can reduce postprandial glucose and lipid levels in able‐bodied individuals. The effects in people with paraplegia are unknown. The study aims were to examine the acute postprandial glucose (primary aim), lipid, blood pressure, and psychological responses (secondary aims) to breaking up prolonged sedentary time in individuals with paraplegia. This was a randomized crossover design trial. Fourteen participants with paraplegia (age 51 ± 9 years, trunk fat mass 44.3 ± 7.7%) took part in the following two, 5.5‐hour conditions: (1) uninterrupted sedentary time (SED), and (2) sedentary time interrupted with 2 minutes of moderate‐intensity arm crank ergometer physical activity every 20 minutes (SED‐ACT). Standardized breakfast and lunch test meals were consumed during each condition. The outcomes were compared between conditions using linear mixed models. Glucose area under the curve (AUC) was significantly lower during the lunch postprandial period in SED‐ACT vs SED (incremental AUC 1.9 [95% CI 1.0, 2.7) and 3.0 [2.1, 3.9] mmol/L∙2.5 hour, respectively, P = .015, f = 0.34). There were no differences between conditions for the breakfast or total 5.5 hours postprandial periods (P > .05). Positive affect was higher in SED‐ACT than SED (P = .001). Breaking up prolonged sedentary time acutely attenuates lunch postprandial glucose and improves positive affect in people with paraplegia. This may have clinical relevance for reducing CVD risk and improving psychological well‐being in this population.
Funding
Heart Research UK. Grant Number: RG2655/17/18
History
School
- Sport, Exercise and Health Sciences
Published in
Scandinavian Journal of Medicine and Science in SportsVolume
30Issue
8Pages
1398 - 1408Publisher
WileyVersion
- VoR (Version of Record)
Rights holder
© The AuthorsPublisher statement
This is an open access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.Acceptance date
2020-03-24Publication date
2020-04-21Copyright date
2020ISSN
0905-7188eISSN
1600-0838Publisher version
Language
- en