Air plasma coupled with antibody-conjugated nanoparticles: a new weapon against cancer
journal contribution
posted on 2013-09-04, 13:01authored byG.C. Kim, G.J. Kim, S.R. Park, S.M. Jeon, H.J. Seo, Felipe IzaFelipe Iza, Jae Koo Lee
Ambient air plasmas have been known to kill cancer cells. To enhance selectivity we have used antibody-conjugated nanoparticles. We achieved five times enhancement of melanoma cell death over the case of the plasma alone by using an air plasma with gold nanoparticles bound to anti-FAK antibodies. Our results show that this new interdisciplinary technique has enormous potential for use as a complement to conventional therapies.
History
School
Mechanical, Electrical and Manufacturing Engineering
Citation
KIM, G.C. ... et al., 2009. Air plasma coupled with antibody-conjugated nanoparticles: a new weapon against cancer. Journal of Physics D: Applied Physics, 42 (3), 032005, doi:10.1088/0022-3727/42/3/032005