Synlett tetrahydroisoquinolines revised Lupin.pdf (550.3 kB)
An Au(I)-catalysed allenamide cyclisation giving access to an α-vinyl-substituted tetrahydroisoquinoline building block
journal contribution
posted on 2014-01-09, 14:32 authored by Sanjitpal Singh, Mark ElsegoodMark Elsegood, Marc KimberMarc KimberAn Au(I)-catalysed intramolecular hydroarylation of an enantiopure allenamide has been achieved and has given access to a key α-vinyl- substititued tetrahydroisoquinoline. Additionally this has been accomplished in very high yield and high diastereoselectivity. © Georg Thieme Verlag Stuttgart · New York.
History
School
- Science
Department
- Chemistry
Citation
SINGH, S., ELSEGOOD, M.R.J. and KIMBER, M.C., 2012. An Au(I)-catalysed allenamide cyclisation giving access to an α-vinyl-substituted tetrahydroisoquinoline building block. Synlett, 23 (4), pp. 565 - 568Publisher
© Georg Thieme VerlagVersion
- AM (Accepted Manuscript)
Publication date
2012Notes
This article was published in the journal, Synlett [© Georg Thieme Verlag]. The definitive version is available at: http://dx.doi.org/10.1055/s-0031-1290335ISSN
0936-5214eISSN
1437-2096Publisher version
Language
- en