Lactone paper JOC Lupin.pdf (647.04 kB)
Download fileAn asymmetric synthesis of trans-fused butyrolactones from endoperoxides
journal contribution
posted on 2014-01-09, 13:54 authored by Joshua Priest, Mark R. Longland, Mark ElsegoodMark Elsegood, Marc KimberMarc KimberThe intermolecular addition of 1,3-dicarbonyl equivalents to endoperoxides in the presence of an organocatalyst yields trans-fused butyrolactones in high yield and enantioselectivities. This methodology expands the synthetic utility of endoperoxides and further underlines their potential as sources of oxygen functionality for natural and non-natural product target synthesis.
History
School
- Science
Department
- Chemistry
Citation
PRIEST, J. ... et al, 2013. An asymmetric synthesis of trans-fused butyrolactones from endoperoxides. Journal of Organic Chemistry, 78 (7), pp. 3476 - 3481Publisher
© American Chemical SocietyVersion
- AM (Accepted Manuscript)
Publication date
2013Notes
This article is closed access until April 2014, it was published in the serial Journal of Organic Chemistry [© American Chemical Society]. The definitive version is available at: http://dx.doi.org/10.1021/jo400177jISSN
0022-3263Publisher version
Language
- en