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An atomic finite element model for biodegradable polymers. Part 2. A model for change in Young’s modulus due to polymer chain scission

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journal contribution
posted on 02.10.2017, 09:05 by Andy GleadallAndy Gleadall, Jingzhe Pan, Marc-Anton Kruft
Atomic simulations were undertaken to analyse the effect of polymer chain scission on amorphous poly(lactide) during degradation. Many experimental studies have analysed mechanical properties degradation but relatively few computation studies have been conducted. Such studies are valuable for supporting the design of bioresorbable medical devices. Hence in this paper, an Effective Cavity Theory for the degradation of Young's modulus was developed. Atomic simulations indicated that a volume of reduced-stiffness polymer may exist around chain scissions. In the Effective Cavity Theory, each chain scission is considered to instantiate an effective cavity. Finite Element Analysis simulations were conducted to model the effect of the cavities on Young's modulus. Since polymer crystallinity affects mechanical properties, the effect of increases in crystallinity during degradation on Young's modulus is also considered. To demonstrate the ability of the Effective Cavity Theory, it was fitted to several sets of experimental data for Young's modulus in the literature.

Funding

Andrew Gleadall acknowledges an EPSRC PhD studentship and a partial University studentship by the University of Leicester, United Kingdom.

History

School

  • Mechanical, Electrical and Manufacturing Engineering

Published in

Journal of the Mechanical Behavior of Biomedical Materials

Volume

51

Pages

237 - 247

Citation

GLEADALL, A. ... et al., 2015. An atomic finite element model for biodegradable polymers. Part 2. A model for change in Young’s modulus due to polymer chain scission. Journal of the Mechanical Behavior of Biomedical Materials, 51, pp.237-247.

Publisher

© Elsevier

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Acceptance date

15/07/2015

Publication date

2015-07-31

ISSN

1751-6161

eISSN

1878-0180

Language

en