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Anatomical flow phantoms of the nonplanar carotid bifurcation, part 1: computer-aided design and fabrication
journal contribution
posted on 2014-10-17, 10:55 authored by Darren WattsDarren Watts, C.J. Sutcliffe, R.H. Morgan, S. Meagher, J. Wardlaw, M. Connell, M.E. Bastin, I. Marshall, K.V. Ramnarine, P. Hoskins, R.A. BlackDoppler ultrasound is widely used in the diagnosis and monitoring of arterial disease. Current clinical
measurement systems make use of continuous and pulsed ultrasound to measure blood flow velocity; however,
the uncertainty associated with these measurements is great, which has serious implications for the screening of
patients for treatment. Because local blood flow dynamics depend to a great extent on the geometry of the affected
vessels, there is a need to develop anatomically accurate arterial flow phantoms with which to assess the accuracy
of Doppler blood flow measurements made in diseased vessels. In this paper, we describe the computer-aided
design and manufacturing (CAD-CAM) techniques that we used to fabricate anatomical flow phantoms based on
images acquired by time-of-flight magnetic resonance imaging (TOF-MRI). Three-dimensional CAD models of
the carotid bifurcation were generated from data acquired from sequential MRI slice scans, from which solid
master patterns were made by means of stereolithography. Thereafter, an investment casting procedure was used
to fabricate identical flow phantoms for use in parallel experiments involving both laser and Doppler ultrasound
measurement techniques.
Funding
EPSRC
History
School
- Mechanical, Electrical and Manufacturing Engineering
Published in
Journal of Ultrasound in Medicine & BiologyVolume
33Issue
(2)Pages
296 - 302Citation
WATTS, D.M. ... et al., 2007. Anatomical flow phantoms of the nonplanar carotid bifurcation, part 1: computer-aided design and fabrication. Journal of Ultrasound in Medicine & Biology, 33 (2), pp. 296 - 302.Publisher
Elsevier © World Federation for Ultrasound in Medicine & BiologyVersion
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2007Notes
This article is closed access.Publisher version
Language
- en