Body composition reference charts for infants from birth to 24 months: Multicenter Infant Body Composition Reference Study
Background: Body composition assessment in the first 2 y of life provides important insights for child nutrition and health. The application and interpretation of body composition data in infants and young children has been challenged by a lack of global reference data.
Objective: To develop body composition reference charts from 0-6 mo based on air displacement plethysmography (ADP) and 3-24 mo based on total body water (TBW) by deuterium dilution (DD).
Method: Body composition was assessed by ADP in infants aged 0-6 mo from Australia, India and South Africa. TBW using DD was assessed for infants aged 3 to 24 mo from Brazil, Pakistan, South Africa and Sri Lanka. Reference charts and centiles were constructed for body composition using the lambda-mu-sigma method (LMS).
Results: Sex-specific reference charts were produced for fat mass index (FMI), fat-free mass index (FFMI), and percent fat mass (%FM) for 0-6 mo (n = 470 infants; 1,899 observations) and 3-24 mo (n = 1,026 infants; 3,690 observations). When compared to other available references, there were observable differences but similar patterns in trajectories of FMI, FFMI and %FM.
Conclusion: These reference charts will strengthen the interpretation and understanding of body composition in infants across the first 24 mo of life.
International Atomic Energy Agency (CRP E43028)
To better understand growth and development of infants and young children in Africa, South East Asia, Western Pacific and Latin America
Bill & Melinda Gates FoundationFind out more...
National Institute for Health Research (NIHR) Leicester Biomedical Research Centre
- Sport, Exercise and Health Sciences
Published inThe American Journal of Clinical Nutrition
- VoR (Version of Record)
Rights holder© The Authors
Publisher statementThis is an Open Access Article. It is published by Elsevier under the Creative Commons Attribution 4.0 International Licence (CC BY). Full details of this licence are available at: https://creativecommons.org/licenses/by/4.0/