CFD and kinetic-based modelling to optimize the sparger design of a large-scale photobioreactor for scaling up of biofuel production.pdf (1.57 MB)Download file
CFD and kinetic‐based modeling to optimize the sparger design of a large‐scale photobioreactor for scaling up of biofuel production
journal contributionposted on 2019-08-13, 13:50 authored by Haider Ali, Jannike Solsvik, Jonathan WagnerJonathan Wagner, Dongda Zhang, Klaus Hellgardt, Cheol Woo Park
Microalgal biofuels have not yet achieved wide‐spread commercialization, partially as a result of the complexities involved with designing and scaling up of their biosystems. The sparger design of a pilot‐scale photobioreactor (120 L) was optimized to enable the scale‐up of biofuel production. An integrated model coupling computational fluid dynamics and microalgal biofuel synthesis kinetics was used to simulate the biomass growth and novel biofuel production (i.e., bisabolene) in the photobioreactor. Bisabolene production from Chlamydomonas reinhardtii mutant was used as an example to test the proposed model. To select the optimal sparger configuration, a rigorous procedure was followed by examining the effects of sparger design parameters (number and diameter of sparger holes and gas flow rates) on spatially averaged bubble volume fraction, light intensity, friction velocity, power input, biomass concentration, and bisabolene production. The optimized sparger design increases the final biomass concentration by 18%, thereby facilitating the scaling up of biofuel production.
National Research Foundation of Korea (NRF)
Korea government. Grant Number: 2017R1A2B2005515
Priority Research Centers Program
MEST. Grant Number: 2010–0020089
- Aeronautical, Automotive, Chemical and Materials Engineering
- Chemical Engineering
Published inBiotechnology and Bioengineering
Pages2200 - 2211
- AM (Accepted Manuscript)
Rights holder© Wiley Periodicals, Inc.
Publisher statementThis is the peer reviewed version of the following article: Ali H, Solsvik J, Wagner JL, Zhang D,Hellgardt K, Park CW. CFD and kinetic‐based modeling tooptimize the sparger design of a large‐scale photobioreactor forscaling up of biofuel production.Biotechnology and Bioengineering.2019;116:2200–2211, which has been published in final form at https://doi.org/10.1002/bit.27010. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.