Carbohydrate-derived iminium salt organocatalysts for the asymmetric epoxidation of alkenes

Page, Philip C. Bulman; Chan, Yohan; Liddle, John; Elsegood, Mark

1-s2.0-S0040402014010667-main.pdf (2.82 MB)

Carbohydrate-derived iminium salt organocatalysts for the asymmetric epoxidation of alkenes

journal contribution

posted on 20.07.2015, 15:38 authored by Philip C. Bulman Page, Yohan Chan, John Liddle, Mark ElsegoodMark Elsegood

A new family of carbohydrate-based dihydroisoquinolinium salts has been prepared and tested for potential as asymmetric catalysts for the epoxidation of unfunctionalized alkene substrates, providing up to 57% ee in the product epoxides.

Funding

This work was supported by Loughborough University, the Engineering and Physical Sciences Research Council, GlaxoSmithKline (CASE award), and The Royal Society (P.C.B.P.: Industry Fellowship).

History

School

Science

Department

Chemistry

Published in

TETRAHEDRON

Volume

70

Issue

40

Pages

7283 - 7305 (23)

Citation

PAGE, P.C.B. ... et al, 2014. Carbohydrate-derived iminium salt organocatalysts for the asymmetric epoxidation of alkenes. Tetraheddron, 70 (40), pp.7283-7305

Publisher

Version

VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution 4.0 International (CC BY 4.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/ by/4.0/