posted on 2015-07-20, 15:38authored byPhilip C. Bulman Page, Yohan Chan, John Liddle, Mark ElsegoodMark Elsegood
A new family of carbohydrate-based dihydroisoquinolinium salts has been prepared and tested for potential as asymmetric catalysts for the epoxidation of unfunctionalized alkene substrates, providing up to 57% ee in the product epoxides.
Funding
This work was supported by Loughborough
University, the Engineering and Physical Sciences Research Council,
GlaxoSmithKline (CASE award), and The Royal Society (P.C.B.P.: Industry Fellowship).
History
School
Science
Department
Chemistry
Published in
TETRAHEDRON
Volume
70
Issue
40
Pages
7283 - 7305 (23)
Citation
PAGE, P.C.B. ... et al, 2014. Carbohydrate-derived iminium salt organocatalysts for the asymmetric epoxidation of alkenes. Tetraheddron, 70 (40), pp.7283-7305
This work is made available according to the conditions of the Creative Commons Attribution 4.0 International (CC BY 4.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/ by/4.0/
Publication date
2014
Notes
This is an Open Access Article. It is published by Elsevier as Open Access at: http://dx.doi.org/10.1016/j.tet.2014.07.052