Carbohydrate-derived iminium salt organocatalysts for the asymmetric epoxidation of alkenes
journal contributionposted on 20.07.2015, 15:38 by Philip C. Bulman Page, Yohan Chan, John Liddle, Mark ElsegoodMark Elsegood
A new family of carbohydrate-based dihydroisoquinolinium salts has been prepared and tested for potential as asymmetric catalysts for the epoxidation of unfunctionalized alkene substrates, providing up to 57% ee in the product epoxides.
This work was supported by Loughborough University, the Engineering and Physical Sciences Research Council, GlaxoSmithKline (CASE award), and The Royal Society (P.C.B.P.: Industry Fellowship).