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Catalytic prenylation of natural polyphenols

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journal contribution
posted on 2023-11-14, 15:29 authored by Yi Du, Iman Korchi, Aleksandr Rubtsov, Andrei MalkovAndrei Malkov

Prenylated polyphenols occur naturally and exhibit biological activity superior to the ubiquitous parent polyphenols. However, their low abundance limits the wider application of these derivatives. In this work, we present an expedient, single-step catalytic protocol for introducing terpene fragments into the aromatic rings of the widely available natural stilbenoids and flavonoids to upgrade their therapeutic potential.

Funding

BENIGN CASCADE EXTRACTIVE BIOREFINERY FOR CONVERTING AGRI-FOOD SIDE STREAMS INTO HIGH-VALUE POLYPHENOLIC BIOACTIVES AND FUNCTIONAL FIBRES FOR PHARMA, COSMECEUTICALS, NUTRACEUTICALS AND FOOD PRODUCTS

European Commission

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Perm Research and Education Centre ‘‘Rational Subsoil Use’’, 2023

History

School

  • Science

Department

  • Chemistry

Published in

New Journal of Chemistry

Volume

47

Issue

44

Pages

20358-20362

Publisher

Royal Society of Chemistry (RSC)

Version

  • VoR (Version of Record)

Rights holder

© The Authors

Publisher statement

This is an Open Access Article. It is published by the Royal Society of Chemistry under the Creative Commons Attribution-NonCommercial 3.0 Unported Licence (CC BY-NC). Full details of this licence are available at: https://creativecommons.org/licenses/by-nc/3.0/

Acceptance date

2023-10-19

Publication date

2023-10-20

Copyright date

2023

ISSN

1144-0546

eISSN

1369-9261

Language

  • en

Depositor

Prof Andrei Malkov. Deposit date: 25 October 2023

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