Chiral counterion strategy in Cu-catalyzed asymmetric allylic oxidation of linear alkenes

Incerti-Pradillos, Celia A.; Hudson, Daniel; Malkov, Andrei

Chiral counterion strategy in Cu-catalyzed asymmetric allylic oxidation of linear alkenes

journal contribution

posted on 2016-05-23, 10:10 authored by Celia A. Incerti-Pradillos, Daniel Hudson, Andrei MalkovAndrei Malkov

Application of a chiral counter-ion strategy in the Kharasch-Sosnovsky reaction is reported. Copper(I) phosphates obtained from axially chiral, BINOL-derived phosphoric acids were investigated as catalysts in the enantioselective allylic oxidation of acyclic alkenes. Good yields and high regioselectivity towards branched allylic ester have been achieved. The chiral phosphates investigated exhibited modest enantioselectivities.

History

School

Science

Department

Chemistry

Published in

Asymmetric Catalysis

Volume

2

Issue

1

Citation

INCERTI-PRADILLOS, C.A., HUDSON, D. and MALKOV, A.V., 2015. Chiral counterion strategy in Cu-catalyzed asymmetric allylic oxidation of linear alkenes. Asymmetric Catalysis, 2(1): pp. 45-50.

Publisher

De Gruyter Open

Version

VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Unported (CC BY-NC-ND 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-nd/3.0/

Publication date

2015-01-25

Notes

This is an Open Access Article. It is published by De Guyter Open under the Creative Commons Attribution 3.0 Unported Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/