Construction of macrocyclic thiodepsipeptides: synthesis of a nosiheptide 'southern hemisphere' model system
journal contribution
posted on 2014-01-08, 14:59 authored by Marc KimberMarc Kimber, Christopher J. MoodyA 20-membered macrocyclic thiodepsipeptide has been synthesized as a model for the southern hemisphere of nosiheptide, the key steps being assembly of an acyclic precursor by amide coupling of indole and thiazole fragments followed by formation of the thiolactone in the macrocyclization step.
History
School
- Science
Department
- Chemistry
Citation
KIMBER, M.C. and MOODY, C.J., 2008. Construction of macrocyclic thiodepsipeptides: synthesis of a nosiheptide 'southern hemisphere' model system. Chemical Communications, (5), pp. 591 - 593.Publisher
© The Royal Society of ChemistryVersion
- VoR (Version of Record)
Publication date
2008Notes
This article is closed access, it was published in the journal Chemical Communications [© The Royal Society of Chemistry]. The definitive version is available at: http://dx.doi.org/10.1039/b715644hISSN
1359-7345Publisher version
Language
- en
