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2022 - Rankin-Turner & Heaney - LCGC.pdf (716.17 kB)

Deployable mass spectrometry for rapid on-site bioanalysis

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journal contribution
posted on 2023-02-17, 12:05 authored by Stephanie Rankin-Turner, Liam HeaneyLiam Heaney
Benchtop liquid chromatography (LC)–mass spectrometry (LC–MS) and benchtop gas chromatography–MS (GC–MS) have been the gold standard in bioanalysis for decades, employed in clinical, forensic, and anti-doping laboratories worldwide. However, traditional instrumentation is subject to limitations that severely restrict the speed at which samples can be analyzed, the ease with which materials can be prepared, and the location where the analysis must be performed. With the advent of ambient ionization and portable mass spectrometers, the ability to perform rapid, on-site analysis is fast becoming a reality. Without the need for extensive sample preparation, analysis times as low as several seconds, and the ability to perform analysis remote from the laboratory, deployable mass spectrometers have the potential to revolutionize bioanalysis. However, several challenges must be tackled before this innovative technology can be widely adopted.

History

School

  • Sport, Exercise and Health Sciences

Published in

LCGC North America

Volume

40

Issue

s7

Pages

14 - 18

Publisher

MultiMedia Pharma Sciences, LLC

Version

  • VoR (Version of Record)

Rights holder

© MultiMedia Pharma Sciences, LLC

Publication date

2022-07-01

Copyright date

2022

ISSN

1527-5949

eISSN

1939-1889

Language

  • en

Depositor

Dr Liam Heaney. Deposit date: 15 February 2023

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