Exp Mech 2016-04-11.pdf (3.19 MB)
Depth-resolved full-field measurement of corneal deformation by optical coherence tomography and digital volume correlation
journal contribution
posted on 2016-04-22, 09:00 authored by Jiawei Fu, Maryam Haghighi Abyaneh, Fabrice Pierron, Pablo RuizPablo RuizThe study of vertebrate eye cornea is an interdisciplinary subject and the research on its mechanical properties has significant importance in ophthalmology. The measurement of depth-resolved 3D full-field deformation behaviour of cornea under changing intraocular pressure is a useful method to study the local corneal mechanical properties. In this work, optical coherence tomography was adopted to reconstruct the internal structure of a porcine cornea inflated from 15 to 18.75 mmHg (close to the physical porcine intraocular pressure) in the form of 3D image sequences. An effective method has been developed to correct the commonly seen refraction induced distortions in the optical coherence tomography reconstructions, based on Fermat’s principle. The 3D deformation field was then determined by performing digital volume correlation on these corrected 3D reconstructions. A simple finite element model of the inflation test was developed and the predicted values were compared against digital volume correlation results, showing good overall agreement.
Funding
The authors would like to thank the China Scholarship Council and the Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, for their financial support. Professor Pierron gratefully acknowledges support from the Royal Society and the Wolfson Foundation through a Royal Society Wolfson Research Merit Award.
History
School
- Mechanical, Electrical and Manufacturing Engineering
Published in
Experimental MechanicsVolume
56Pages
1203–1217Citation
FU, J. ... et al., 2016. Depth-resolved full-field measurement of corneal deformation by optical coherence tomography and digital volume correlation. Experimental Mechanics, 56(7), pp. 1203–1217.Publisher
Springer (© Society for Experimental Mechanics)Version
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Acceptance date
2016-04-11Publication date
2016-04-15Copyright date
2016Notes
The final publication is available at Springer via http://dx.doi.org/10.1007/s11340-016-0165-y.ISSN
0014-4851eISSN
1741-2765Publisher version
Language
- en