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Depth-resolved full-field measurement of corneal deformation by optical coherence tomography and digital volume correlation

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journal contribution
posted on 22.04.2016, 09:00 by Jiawei Fu, Maryam Haghighi Abyaneh, Fabrice Pierron, Pablo RuizPablo Ruiz
The study of vertebrate eye cornea is an interdisciplinary subject and the research on its mechanical properties has significant importance in ophthalmology. The measurement of depth-resolved 3D full-field deformation behaviour of cornea under changing intraocular pressure is a useful method to study the local corneal mechanical properties. In this work, optical coherence tomography was adopted to reconstruct the internal structure of a porcine cornea inflated from 15 to 18.75 mmHg (close to the physical porcine intraocular pressure) in the form of 3D image sequences. An effective method has been developed to correct the commonly seen refraction induced distortions in the optical coherence tomography reconstructions, based on Fermat’s principle. The 3D deformation field was then determined by performing digital volume correlation on these corrected 3D reconstructions. A simple finite element model of the inflation test was developed and the predicted values were compared against digital volume correlation results, showing good overall agreement.

Funding

The authors would like to thank the China Scholarship Council and the Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, for their financial support. Professor Pierron gratefully acknowledges support from the Royal Society and the Wolfson Foundation through a Royal Society Wolfson Research Merit Award.

History

School

  • Mechanical, Electrical and Manufacturing Engineering

Published in

Experimental Mechanics

Volume

56

Pages

1203–1217

Citation

FU, J. ... et al., 2016. Depth-resolved full-field measurement of corneal deformation by optical coherence tomography and digital volume correlation. Experimental Mechanics, 56(7), pp. 1203–1217.

Publisher

Springer (© Society for Experimental Mechanics)

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Acceptance date

11/04/2016

Publication date

2016-04-15

Copyright date

2016

Notes

The final publication is available at Springer via http://dx.doi.org/10.1007/s11340-016-0165-y.

ISSN

0014-4851

eISSN

1741-2765

Language

en