Wright Development and evaluation of intervention Programme Grant App Research 2016.pdf (108.08 MB)
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Development and evaluation of an intervention for the prevention of childhood obesity in a multiethnic population: the Born in Bradford applied research programme

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posted on 10.06.2016, 13:06 by John Wright, Lesley Fairley, Rosie R.C. McEachan, Maria Bryant, Emily PetherickEmily Petherick, Pinki Sahota, Gillian Santorelli, Sally E. Barber, Debbie A. Lawlor, Natalie Taylor, Raj Bhopal, Noel Cameron, Jane West, Andrew J. Hill, Carolyn D. Summerbell, Amanda Farrin, Helen Ball, Tamara Brown, Diane Farrar, Neil Small
Background: There is an absence of evidence about interventions to prevent or treat obesity in early childhood and in South Asian populations, in whom risk is higher. Objectives: To study patterns and the aetiology of childhood obesity in a multiethnic population and develop a prevention intervention. Design: A cohort of pregnant women and their infants was recruited. Measures to compare growth and identify targets for obesity prevention, sensitive to ethnic differences, were collected. A feasibility randomised controlled trial (RCT) was undertaken. Setting: Bradford, UK. Participants: A total of 1735 mothers, 933 of whom were of South Asian origin. Intervention: A feasibility trial of a group-based intervention aimed at overweight women, delivered ante- and postnatally, targeting key modifiable lifestyle behaviours to reduce infant obesity. Main outcome measures: The feasibility and acceptability of the pilot intervention. Data sources: Routine NHS data and additional bespoke research data. Review methods: A systematic review of diet and physical activity interventions to prevent or treat obesity in South Asian children and adults. Results: Routine measures of growth were accurate. The prevalence of risk factors differed between mothers of white British ethnicity and mothers of Pakistani ethnicity and weight and length growth trajectories differed between Pakistani infants and white British infants. Prediction equations for risk of childhood obesity were developed. An evidence-based intervention was evaluated in a pilot RCT and was found to be feasible and acceptable. Limitations: This was a single-centre observational study and a pilot evaluation. Conclusions: The programme has been successful in recruiting a unique multiethnic childhood obesity cohort, which has provided new evidence about modifiable risk factors and biethnic growth trajectories. A novel group-based behavioural change intervention has been developed and successfully piloted. A multisite cluster RCT is required to evaluate effectiveness. Trial registration: Current Controlled Trials ISRCTN56735429. Funding: The National Institute for Health Research Programme Grants for Applied Research programme.


The research reported in this issue of the journal was funded by PGfAR as project number RP-PG-0407-10044.



  • Sport, Exercise and Health Sciences

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Programme Grants for Applied Research






1 - 164


WRIGHT, J. ... et al, 2016. Development and evaluation of an intervention for the prevention of childhood obesity in a multiethnic population: the Born in Bradford applied research programme. Programme Grants for Applied Research, 4 (6), pp. 1 - 164.


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© Queen’s Printer and Controller of HMSO 2016. This work was produced by Wright et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.







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