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Download fileEffect of a high and low dose of caffeine on human lymphocyte activation in response to antigen stimulation
journal contribution
posted on 08.03.2016, 15:04 authored by Deborah K. Dulson, Nicolette BishopNicolette BishopThis study investigated the effect of caffeine on antigen-stimulated lymphocyte activation. Six males rested for 3.5 h
after ingesting 0 (PLA), 2, or 6 (6CAF) mg·kg−1 body mass of caffeine. The number of antigen-stimulated NK CD69+ cells increased
in 6CAF at 1 h compared with PLA (P = 0.021). Caffeine did not influence the number of antigen-stimulated CD69+ T cells or the
geometric mean fluorescence intensity expression of CD69 on antigen-stimulated lymphocytes, suggesting caffeine has little
effect on antigen-stimulated lymphocyte activation.
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