This study investigated the effect of caffeine on antigen-stimulated lymphocyte activation. Six males rested for 3.5 h
after ingesting 0 (PLA), 2, or 6 (6CAF) mg·kg−1 body mass of caffeine. The number of antigen-stimulated NK CD69+ cells increased
in 6CAF at 1 h compared with PLA (P = 0.021). Caffeine did not influence the number of antigen-stimulated CD69+ T cells or the
geometric mean fluorescence intensity expression of CD69 on antigen-stimulated lymphocytes, suggesting caffeine has little
effect on antigen-stimulated lymphocyte activation.
School
- Sport, Exercise and Health Sciences
Published in
APPLIED PHYSIOLOGY NUTRITION AND METABOLISMVolume
41Issue
2Pages
224 - 227Citation
DULSON, D.K. and BISHOP, N., 2016. Effect of a high and low dose of caffeine on human lymphocyte activation in response to antigen stimulation. Applied Physiology Nutrition and Metabolism, 41 (2), pp. 224 - 227.Publisher
NRC Research PressVersion
AM (Accepted Manuscript)Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2015-10-29Notes
This is the accepted version of an article subsequently published in the journal, Applied Physiology, Nutrition, and Metabolism. The definitive version is available at: http://dx.doi.org/10.1139/apnm-2015-0456.ISSN
1715-5312Language
en
CC BY-NC-ND 4.0