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Effect of balloon pre-dilation on performance of self-expandable nitinol stent in femoropopliteal artery

journal contribution
posted on 22.09.2022, 15:06 authored by Ran HeRan He, Liguo ZhaoLiguo Zhao, Vadim SilberschmidtVadim Silberschmidt

Balloon pre-dilation is usually performed before implantation of a nitinol stent in a femoropopliteal artery in a case of severe blockage or calcified plaque. However, its effect on performance of the nitinol stent in a diseased femoropopliteal artery has not been studied yet. This study compares the outcomes of stenting with pre-dilation and without it by modelling the entire processes of stent deployment. Fatigue deformation of the implanted stent is also modelled under diastolic-systolic blood pressure, repetitive bending, torsion, axial compression and their combination. Reduced level of stress in the stent occurs after stenting with pre-dilation, but causing the increased damage in the media layer, i.e., the middle layer of the arterial wall. Generally, pre-dilation increases the risk of nitinol stent’s fatigue failure. Additionally, the development of in-stent restenosis is predicted based on the stenting-induced tissue damage in the media layer, and no severe mechanical irritation is induced to the media layer by pre-dilation, stent deployment or fatigue loading.

Funding

Smart Peripheral Stents for the Lower Extremity - Design, Manufacturing and Evaluation

Engineering and Physical Sciences Research Council

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History

School

  • Mechanical, Electrical and Manufacturing Engineering

Published in

Biomechanics and Modeling in Mechanobiology

Publisher

Springer

Version

AM (Accepted Manuscript)

Publisher statement

This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/[insert DOI]

Acceptance date

19/09/2022

ISSN

1617-7959

eISSN

1617-7940

Language

en

Depositor

Dr Ran He. Deposit date: 22 September 2022