Effect of breakfast omission on subjective appetite, metabolism, acylated ghrelin and GLP-1(7-36) during rest and exercise
journal contributionposted on 2016-04-07, 08:43 authored by David Clayton, David StenselDavid Stensel, Lewis JamesLewis James
OBJECTIVES. Breakfast omission induces compensatory eating behaviour at lunch, but often reduces daily energy intake. This study investigated the effect of breakfast omission on within-day subjective appetite, energy expenditure, substrate utilisation, and appetite hormone profiles, in response to standardised feeding and exercise. METHODS. Eight male, habitual breakfast eaters completed two randomised trials. Subjects arrived overnight fasted (0 h), and either consumed (BC) or omitted (BO) a standardized breakfast (mean standard deviation [SD]) (3085  kJ). Lunch (4162  kJ) and dinner (4914  kJ) were provided at 4.5 and 10 h, respectively and subjects performed 60 min fixed-intensity cycling (50% VO2 peak) at 8 h. Blood samples were collected at 0, 4.5, 6, and 8 h, with expired air and subjective appetite sensations (hunger, fullness, desire to eat (DTE), and prospective food consumption [PFC]) collected throughout. Heart rate and perceived exertion were measured during exercise. RESULTS. Hunger, DTE and PFC were greater and fullness lower during BO (P < 0.05) between breakfast and lunch, with no differences after lunch (P > 0.193). Resting energy expenditure was greater at 2.5 h during BC (P < 0.05) with no other differences between trials (P > 0.156). Active glucogon-like peptide-1 (GLP-17-36) was greater (P < 0.05) and acylated ghrelin tended to be greater (P = 0.078) at 4.5 h during BC. Heart rate was greater on BO (P < 0.05) during exercise. CONCLUSIONS. The results of this laboratory-controlled study suggest that the effects of breakfast omission are transient and do not extend beyond lunch, even when the negative energy balance created by breakfast omission is sustained via standardised feeding and exercise.
- Sport, Exercise and Health Sciences
Pages179 - 185 (7)
CitationCLAYTON, D.J., STENSEL, D.J. and JAMES, L.J., 2016. Effect of breakfast omission on subjective appetite, metabolism, acylated ghrelin and GLP-1(7-36) during rest and exercise. Nutrition, 32 (2), pp.179-185.
- AM (Accepted Manuscript)
Publisher statementThis work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/
NotesThis paper was accepted for publication in the journal Nutrition and the definitive published version is available at http://dx.doi.org/10.1016/j.nut.2015.06.013