s13063-022-06046-w.pdf (1.03 MB)
Download file

Effects of Tai Chi on the neuromuscular function of the patients with functional ankle instability: a study protocol for a randomized controlled trial

Download (1.03 MB)
journal contribution
posted on 10.02.2022, 11:15 by Huiru Tang, Min Mao, Daniel FongDaniel Fong, Qipeng Song, Yan Chen, Zhipeng Zhou, Cui Zhang, Jiangna Wang, Xuewen Tian, Wei Sun

• Background: Ankle instability limits physical activities, and undermines a person’s quality of life. Tai Chi’s health benefits have been reported in different population groups. However, the effects of Tai Chi on neuromuscular function among young adults with functional ankle instability (FAI) remain unclear. Therefore, we aim to investigate the effect of Tai Chi on young adults with FAI.

• Methods: This study will be conducted as a randomized controlled trial with blinded assessors. A total of 104 young adults with FAI will be recruited and randomly assigned to intervention and control groups. The participants in the simplified Tai Chi exercise program (STCEP) group will receive a 12-week Tai Chi training. The participants in the control group will receive a low-intensity exercise program and the health education for 12 weeks. The primary and secondary outcomes will be assessed at baseline, 4th, 8th, and 12th weeks. Primary outcome measures will include the Cumberland Ankle Instability Tool (CAIT) score, kinematics/kinetics data, electromyography during single-leg landing tasks, and the modified Star Excursion Balance Test (mSEBT). Secondary outcome measures will include the total time of Dynamic Leap and Balance Test (DLBT), ankle muscle strength, and ankle proprioception.

• Discussion: This study will investigate the effects of Tai Chi exercise on the neuromuscular function of patients with FAI, as indicated by ankle joint biomechanics, ankle proprioception, balance, ankle muscle strength, and ankle muscle activation. Results will demonstrate that Tai Chi can be an effective exercise for young adults with FAI.

• Trial registration: Chinese Clinical Trial Registry ChiCTR2100044089. Registered on 10 March 2021. https://www.chictr.org.cn


Shandong Provincial Natural Science Foundation (ZR2020QC091)

China Shandong Key Research and Development Plan(2020CXGC010902)

National Natural Science Foundation of China (31700815)



  • Sport, Exercise and Health Sciences

Published in





BioMed Central


VoR (Version of Record)

Rights holder

© The Authors

Publisher statement

This is an Open Access Article. It is published by BioMed Central under the Creative Commons Attribution 4.0 International Licence (CC BY 4.0). Full details of this licence are available at: https://creativecommons.org/licenses/by/4.0/

Acceptance date


Publication date


Copyright date







Dr Daniel Fong. Deposit date: 19 January 2022

Article number