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Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity: RCT

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posted on 14.03.2018 by Helen M. Parretti, Paul Aveyard, Andrew Blannin, Sue J. Clifford, Sarah J. Coleman, Andrea K. Roalfe, Amanda Daley
Objective To investigate the efficacy of water preloading before meals as a weight loss strategy for adults with obesity. Methods A two-group randomized controlled trial was conducted in Birmingham, England. Eighty-four adults with obesity were recruited from general practices. All participants were given a face-to-face weight management consultation at baseline (30 min) and a follow-up telephone consultation at 2 weeks (10 min). At baseline, participants were randomized to either drinking 500 ml of water 30 min before their main meals or an attention control group where participants were asked to imagine their stomach was full before meals. The primary outcome was weight change at 12-week follow-up. Several measures of adherence were also used, including 24 h total urine collections. Results 41 participants were randomized to the intervention group and 43 to the comparator group. The water preloading group lost -1.3 kg (95% CI -2.4 to -0.1, P = 0.028) more than comparators at follow up. Adjusting for ethnicity, deprivation, age, and gender resulted in the intervention group losing -1.2 kg (95% CI -2.4 to 0.07, P = 0.063) more than the comparator. Conclusions There is preliminary evidence that water preloading before main meals leads to a moderate weight loss at follow up. ISRCTN33238158

Funding

Scientific Foundation board of the Royal College of General Practitioners (RCGP), grant number SFB 2013-28, and European Hydration Institute (EHI) Student Research Grant.

History

School

  • Sport, Exercise and Health Sciences

Published in

Obesity

Volume

23

Issue

9

Pages

1785 - 1791

Citation

PARRETTI, H.M. ... et al, 2015. Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity: RCT. Obesity, 23 (9), pp.1785-1791.

Publisher

Wiley © The Obesity Society

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2015

Notes

This is the peer reviewed version of the following article: PARRETTI, H.M. ... et al, 2015. Efficacy of water preloading before main meals as a strategy for weight loss in primary care patients with obesity: RCT. Obesity, 23 (9), pp.1785-1791, which has been published in final form at https://doi.org/10.1002/oby.21167. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

ISSN

1930-7381

eISSN

1930-739X

Language

en

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