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EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging
journal contribution
posted on 2015-09-09, 10:19 authored by Stephen ButlerStephen Butler, Laurent Lamarque, Robert Pal, David ParkerNine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit
excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of
fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo. Their use as
cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the
endoplasmic reticulum of various mammalian cell types.
Funding
We thank the ERC for support (DP, SJB, RP; FCC 266804).
History
School
- Science
Department
- Chemistry
Published in
Chemical ScienceVolume
5Issue
5Pages
1750 - 1756Citation
BUTLER, S.J. ... et al, 2014. EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging. Chemical Science, 5 (5), pp. 1750 - 1756.Publisher
© The Royal Society of ChemistryVersion
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Acceptance date
2013-12-11Publication date
2014-01-27Notes
This article is closed access.ISSN
2041-6520eISSN
2041-6539Publisher version
Language
- en