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EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging
journal contributionposted on 2015-09-09, 10:19 authored by Stephen ButlerStephen Butler, Laurent Lamarque, Robert Pal, David Parker
Nine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo. Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.
We thank the ERC for support (DP, SJB, RP; FCC 266804).
Published inChemical Science
Pages1750 - 1756
CitationBUTLER, S.J. ... et al, 2014. EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging. Chemical Science, 5 (5), pp. 1750 - 1756.
Publisher© The Royal Society of Chemistry
- VoR (Version of Record)
Publisher statementThis work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/
NotesThis article is closed access.