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EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

journal contribution
posted on 09.09.2015, 10:19 by Stephen ButlerStephen Butler, Laurent Lamarque, Robert Pal, David Parker
Nine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo. Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

Funding

We thank the ERC for support (DP, SJB, RP; FCC 266804).

History

School

  • Science

Department

  • Chemistry

Published in

Chemical Science

Volume

5

Issue

5

Pages

1750 - 1756

Citation

BUTLER, S.J. ... et al, 2014. EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging. Chemical Science, 5 (5), pp. 1750 - 1756.

Publisher

© The Royal Society of Chemistry

Version

VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Acceptance date

11/12/2013

Publication date

2014-01-27

Notes

This article is closed access.

ISSN

2041-6520

eISSN

2041-6539

Language

en