ProSI 2020 Fracture Behaviour of Collagen - Effect of Environment.pdf (740.48 kB)

Fracture behaviour of collagen: effect of environment

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journal contribution
posted on 23.03.2021, 16:04 by Shirsha Bose, Simin Li, Elisa Mele, Vadim Silberschmidt
Collagen forms one-third of the human-body proteome and finds a wide range of applications in a biomedical field thanks to its mechanical stability, biocompatibility and biodegradability. Collagen can be produced in a form of films suitable for scaffolds, tissue regeneration, flexible electronics etc. significant differences in the mechanical properties were observed for collagen films tested in-aqua environment. Considering this and potential biomedical applications of collagen films, their mechanical testing should be performed in aqua to mimic the in-vivo conditions. Hence, this study reported the fracture behaviour of collagen in-aqua compared with that at ambient (in-air) loading conditions. Single-edged notched tension (SENT) specimens of collagen films demonstrated completely different stress-strain curves in-aqua conditions. A reduction in their tensile strength (by 90%) and fracture energy (by 40%) accompanied with an increase in the failure strain (by 1600%) was observed for such conditions. Crack propagation was rapid for in-air specimens, with a brittle failure, while for in-aqua specimens the crack opening was rather slow and accompanied with by crack blunting, leading to large plastic deformation (ductile failure). These behaviours encouraged the quantification of the fracture toughness of collagen films using different fracture toughness parameters: KIC (linear elastic fracture mechanics) for in-air specimens and JC-integral (elastic-plastic fracture mechanics) for in-aqua specimens.

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering
  • Mechanical, Electrical and Manufacturing Engineering

Department

  • Materials

Published in

Procedia Structural Integrity

Volume

28

Pages

843 - 849

Publisher

Elsevier BV

Version

VoR (Version of Record)

Rights holder

© The Authors

Publisher statement

This is an Open Access Article. It is published by Elsevier under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (CC BY-NC-ND 4.0). Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2020-12-01

Copyright date

2020

ISSN

2452-3216

eISSN

2452-3216

Language

en

Depositor

Prof Vadim Silberschmidt. Deposit date: 18 March 2021

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Loughborough Publications

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