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High throughput membrane emulsification using a single‐pass annular flow crossflow membrane
journal contribution
posted on 2020-03-17, 14:59 authored by Richard Holdich, Marijana DragosavacMarijana Dragosavac, Bruce Williams, Samuel TrotterMembrane emulsification has the potential to revolutionize the energy-efficient
production of uniform emulsions and dispersions, relevant to diverse fields from
pharmaceutical Active Ingredient controlled release particles to Fast Moving Consumer
Goods. A ovel highly robust single-pass continuous phase crossflow system has been
developed providing dispersed phase concentrations up to 40% v/v and dispersed
phase fluxes up to 5730 l m-2 h-1, from a single 100 mm long membrane tube. Extensive
results of two oil-in-water systems (vegetable oil and PolyCaproLactone dissolved in
DiChloroMethane) and one water-in-oil system (sodium silicate solution) are reported,
using hydrophilic and hydrophobic membranes respectively. Mathematical models are
validated enabling comprehensive engineering analysis of processes including predicted droplet size, membrane pressure drops and energy requirement for dispersion
production. Surfactant depletion, pore utilization and droplet interaction at the
membrane surface were investigated to provide a comprehensive analysis of the
capabilities of novel annular-flow membrane emulsification for high throughput emulsion
generation.
Funding
UK Engineering and Physical Sciences Research Council (EPSRC) grant number EP/P002781/1 ‘Tailoring the micro and meso-porosity of spherical particles using nano/microbubbles as templates
History
School
- Aeronautical, Automotive, Chemical and Materials Engineering
Department
- Chemical Engineering
Published in
AIChE JournalVolume
66Issue
6Publisher
Wiley Periodicals, Inc. on behalf of American Institute of Chemical EngineersVersion
- VoR (Version of Record)
Rights holder
© The AuthorsPublisher statement
This is an open access article. It is published by Wiley under the Creative Commons Attribution 4.0 International Licence (CC BY). Full details of this licence are available at: https://creativecommons.org/licenses/by/4.0/Acceptance date
2020-02-24Publication date
2020-03-30Copyright date
2020ISSN
0001-1541eISSN
1547-5905Publisher version
Language
- en