posted on 2015-09-11, 14:28authored byStephanie Tissot, Martino Reclari, Samuel Quinodoz, Matthieu Dreyer, Dominique T. Monteil, Lucia Baldi, David Hacker, Mohamed Farhat, Marco DiscacciatiMarco Discacciati, Alfio Quarteroni, Florian M. Wurm
Orbitally shaken bioreactors (OSRs) of nominal volume from 50 mL to 2’000 L have been developed for the cultivation of suspension-adapted mammalian cells. Here we study the hydrodynamics of OSRs for mammalian cells. The results are expected to allow the determination of key parameters for cell cultivation conditions and will facilitate the scale-up of OSRs.
History
School
Science
Department
Mathematical Sciences
Published in
BMC proceedings
Volume
5 Suppl 8
Pages
P39 - ?
Citation
TISSOT, S. ... et al, 2011. Hydrodynamic stress in orbitally shaken bioreactors. BMC Proceedings, 5 (Suppl 8), pp. P39.
This work is made available according to the conditions of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/
Publication date
2011
Notes
This is an open access article published by Biomed Central and distributed under the terms of the Creative Commons
Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in
any medium, provided the original work is properly cited.