Hydrodynamic stress in orbitally shaken bioreactors.

Tissot, Stephanie; Reclari, Martino; Quinodoz, Samuel; Dreyer, Matthieu; Monteil, Dominique T.; Baldi, Lucia; Hacker, David; Farhat, Mohamed; Discacciati, Marco; Quarteroni, Alfio; Wurm, Florian M.

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Hydrodynamic stress in orbitally shaken bioreactors.

journal contribution

posted on 11.09.2015, 14:28 authored by Stephanie Tissot, Martino Reclari, Samuel Quinodoz, Matthieu Dreyer, Dominique T. Monteil, Lucia Baldi, David Hacker, Mohamed Farhat, Marco DiscacciatiMarco Discacciati, Alfio Quarteroni, Florian M. Wurm

Orbitally shaken bioreactors (OSRs) of nominal volume from 50 mL to 2’000 L have been developed for the cultivation of suspension-adapted mammalian cells. Here we study the hydrodynamics of OSRs for mammalian cells. The results are expected to allow the determination of key parameters for cell cultivation conditions and will facilitate the scale-up of OSRs.

History

School

Science

Department

Mathematical Sciences

Published in

BMC proceedings

Volume

5 Suppl 8

Pages

P39 - ?

Citation

TISSOT, S. ... et al, 2011. Hydrodynamic stress in orbitally shaken bioreactors. BMC Proceedings, 5 (Suppl 8), pp. P39.

Publisher

Biomed Central / © The Authors

Version

VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/

Publication date

2011

Notes

This is an open access article published by Biomed Central and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.