Hydrodynamic stress in orbitally shaken bioreactors.
journal contributionposted on 2015-09-11, 14:28 authored by Stephanie Tissot, Martino Reclari, Samuel Quinodoz, Matthieu Dreyer, Dominique T. Monteil, Lucia Baldi, David Hacker, Mohamed Farhat, Marco DiscacciatiMarco Discacciati, Alfio Quarteroni, Florian M. Wurm
Orbitally shaken bioreactors (OSRs) of nominal volume from 50 mL to 2’000 L have been developed for the cultivation of suspension-adapted mammalian cells. Here we study the hydrodynamics of OSRs for mammalian cells. The results are expected to allow the determination of key parameters for cell cultivation conditions and will facilitate the scale-up of OSRs.
- Mathematical Sciences
Published inBMC proceedings
Volume5 Suppl 8
PagesP39 - ?
CitationTISSOT, S. ... et al, 2011. Hydrodynamic stress in orbitally shaken bioreactors. BMC Proceedings, 5 (Suppl 8), pp. P39.
PublisherBiomed Central / © The Authors
- VoR (Version of Record)
Publisher statementThis work is made available according to the conditions of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/
NotesThis is an open access article published by Biomed Central and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.