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Impact of a novel home-based exercise intervention on health indicators in inactive premenopausal women: A 12-week randomised controlled trial

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posted on 03.02.2020, 13:43 by Luke J Connolly, Suzanne Scott, Carmelina M Morencos, Jonathan Fulford, Andrew M Jones, Karen Knapp, Peter Krustrup, Stephen BaileyStephen Bailey, Joanna L Bowtell

Purpose: This study tested the hypothesis that a novel, audio-visual-directed, home-based exercise training intervention would be effective at improving cardiometabolic health and mental well-being in inactive premenopausal women. Methods: Twenty-four inactive premenopausal women (39 ± 10 y) were randomly assigned to an audio-visual-directed exercise training group (DVD; n = 12) or control group (CON; n = 12). During the 12-week intervention period, the DVD group performed thrice-weekly training sessions of 15 min. Training sessions comprised varying-intensity movements involving multiplanar whole-body accelerations and decelerations (average heart rate (HR) = 76 ± 3% HRmax). CON continued their habitual lifestyle with no physical exercise. A series of health markers were assessed prior to and following the intervention. Results: Following the DVD intervention, [HDL cholesterol] (Pre: 1.83 ± 0.45, Post: 1.94 ± 0.46 mmol/L) and mental well-being, assessed via the Warwick Edinburgh Mental Well-Being Scale, improved (P<0.05). Conversely, [LDL cholesterol], [triglycerides], fasting [glucose], body composition and resting blood pressure and HR were unchanged following the DVD intervention (P>0.05). There were no pre-post intervention changes in any of the outcome variables in the CON group (P>0.05). Conclusion: The present study suggests that a novel, audio-visual-directed exercise training intervention, consisting of varied-intensity movements interspersed with spinal and lower limb mobility and balance tasks, can improve [HDL cholesterol] and mental well-being in premenopausal women. Therefore, home-based, audio-visual-directed exercise training (45 min/week) appears to be a useful tool to initiate physical activity and improve aspects of health in previously inactive premenopausal women.



  • Sport, Exercise and Health Sciences

Published in

European Journal of Applied Physiology




771 - 782


Springer Verlag


AM (Accepted Manuscript)

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© Springer-Verlag GmbH Germany, part of Springer Nature

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This is a post-peer-review, pre-copyedit version of an article published in European Journal of Applied Physiology. The final authenticated version is available online at:

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Dr Stephen Bailey Deposit date: 2 February 2020