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Influence of muscle mass in the assessment of lower limb strength in COPD: validation of the prediction equation
journal contribution
posted on 2017-10-20, 10:33 authored by Ruth Pearson, Dale EsligerDale Esliger, Emily PetherickEmily Petherick, Rachel A. Evans, N. Greening, B. James, Andrew KingsnorthAndrew Kingsnorth, Mike Morgan, Mark W. Orme, Lauren SherarLauren Sherar, Sally Singh, N. Toms, Michael SteinerAbsence of established reference values limits application of quadriceps maximal voluntary contraction (QMVC) measurement. The impact of muscle mass inclusion in predictions is unclear. Prediction equations encompassing gender, age and size with (FFM+) and without (FFM−), derived in healthy adults (n=175), are presented and compared in two COPD cohorts recruited from primary care (COPD-PC, n=112) and a complex care COPD clinic (COPD-CC, n=189). Explained variance was comparable between the prediction models (R2: FFM+: 0.59, FFM−: 0.60) as were per cent predictions in COPD-PC (88.8%, 88.3%). However, fat-free mass inclusion reduced the prevalence of weakness in COPD, particularly in COPD-CC where 11.9% fewer were deemed weak.
History
School
- Sport, Exercise and Health Sciences
Published in
ThoraxPages
thoraxjnl-2016-209870 - thoraxjnl-2016-209870Citation
TRETHEWEY, R. ... et al, 2018. Influence of muscle mass in the assessment of lower limb strength in COPD: validation of the prediction equation. Thorax, 73(6), pp. 587-589.Publisher
BMJ Publishing Group © Article author(s)Version
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc/4.0/Publication date
2017-09-02Notes
This article was published in the journal, Thorax [BMJ Publishing Group © Article author(s)] and the definitive version is available at: https://doi.org/10.1136/thoraxjnl-2016-209870ISSN
0040-6376eISSN
1468-3296Publisher version
Language
- en