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Isoxazole to oxazole: a mild and unexpected transformation
journal contribution
posted on 2015-02-27, 11:02 authored by Ray Jones, Alexander Chatterley, Romain Marty, W. Martin Owton, Mark ElsegoodMark Elsegood3-Aryltetrahydrobenzisoxazoles prepared en route to the coleophomone natural products and analogues, were found to undergo a remarkable base-mediated rearrangement to 2-aryltetrahydrobenzoxazoles. The scope of this unprecedented, facile transformation was probed: a range of analogues was produced, a mechanism proposed, and an application demonstrated by synthesis of a known herbicidal compound.
History
School
- Science
Department
- Chemistry
Published in
CHEMICAL COMMUNICATIONSVolume
51Issue
6Pages
1112 - 1115 (4)Citation
JONES, R.C.F. ... et al., 2015. Isoxazole to oxazole: a mild and unexpected transformation. Chemical Communications, 51 (6), pp. 1112 - 1115.Publisher
Royal Society of ChemistryVersion
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/Publication date
2015Notes
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.ISSN
1359-7345Publisher version
Language
- en
