Kinetic resolution in asymmetric epoxidation using iminium salt catalysis
journal contribution
posted on 2015-02-25, 11:36 authored by Philip C. Bulman Page, Louise F. Appleby, Yohan Chan, David P. Day, Benjamin BuckleyBenjamin Buckley, Alexandra M.Z. Slawin, Steven M. Allin, Michael J. McKenzieThe first reported examples of kinetic resolution in epoxidation reactions using iminium salt catalysis are described, providing up to 99% ee in the epoxidation of racemic cis-chromenes.
Funding
This investigation has enjoyed the support of the EPSRC, the University of East Anglia, Charnwood Molecular Ltd, and the ERDF (IS:CE-Chem & INTERREG IVa Programme 4061). We acknowledge the support of The Royal Society (PCBP: Industry Fellowship). We are also indebted to the EPSRC Mass Spectrometry Unit, Swansea.
History
School
- Science
Department
- Chemistry
Published in
JOURNAL OF ORGANIC CHEMISTRYVolume
78Issue
16Pages
8074 - 8082 (9)Citation
PAGE, P.C.B. ... et al., 2013. Kinetic resolution in asymmetric epoxidation using iminium salt catalysis. Journal of Organic Chemistry, 78 (16), pp. 8074 - 8082.Publisher
American Chemical SocietyVersion
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution 4.0 International (CC BY 4.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/ by/4.0/Publication date
2013Notes
This is an Open Access Article. It is published by the American Chemical Society under the Creative Commons Attribution 4.0 Unported Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/4.0/ISSN
0022-3263Publisher version
Language
- en
