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Lethality mechanisms in Escherichia coli induced by intense sub-microsecond electrical pulses

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posted on 20.08.2009, 15:15 by Priya R. Chalise, Stefano Perni, Gilbert Shama, Bucur M. Novac, Ivor R. Smith, Michael G. Kong
In this letter, the authors present the inactivation kinetics of cells of Escherichia coli and its mutants following treatment with high-intensity electrical pulses of 700 and 32 ns durations. Their experimental results suggest that bacterial inactivation by 700 ns pulses is consistent with a mechanism of reversible electroporation, whereas inactivation by 32 ns pulses may occur as a result of damage to intracellular components. They believe that their results represent a first step towards elucidating the mechanism of lethality of submicrosecond pulses of different durations in prokaryotes.

History

School

  • Mechanical, Electrical and Manufacturing Engineering

Citation

CHALISE, P.R. ... et al, 2006. Lethality mechanisms in Escherichia coli induced by intense sub-microsecond electrical pulses. Applied Physics Letters, 89 (15), article 153902, pp.1-3.

Publisher

© American Institute of Physics

Version

VoR (Version of Record)

Publication date

2006

Notes

Copyright 2006 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the authors and the American Institute of Physics. This article appeared in the journal, Applied Physics Letters, and may be found at: http://link.aip.org/link/?APPLAB/89/153902/1

ISSN

0003-6951;1077-3118

Language

en