Low-field benchtop NMR spectroscopy as a potential non-stationary tool for point-of-care urinary metabolite tracking in diabetic conditions

Edgar, Mark; Percival, Benita C; Gibson, Miles; Jafari, Fereshteh; Grootveld, Martin

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Low-field benchtop NMR spectroscopy as a potential non-stationary tool for point-of-care urinary metabolite tracking in diabetic conditions

journal contribution

posted on 13.05.2021, 12:31 by Mark EdgarMark Edgar, Benita C Percival, Miles Gibson, Fereshteh Jafari, Martin Grootveld

We describe the advantages and diagnostic/prognostic significance of low-field, near-portable benchtop NMR spectrometers for the multicomponent metabolomics analysis of targeted and untargeted urinary biomarkers (≥15) in type 2 diabetes patients. Implementation of these facilities at ‘point-of-care’ clinical sites may yield valuable advantages for the sequential monitoring of diabetic and prediabetic individuals.

History

School

Science

Department

Chemistry

Published in

Diabetes Research and Clinical Practice

Volume

171

Publisher

Elsevier BV

Version

P (Proof)

Rights holder

Publisher statement

This paper was accepted for publication in the journal Diabetes Research and Clinical Practice and the definitive published version is available at https://doi.org/10.1016/j.diabres.2020.108554.