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Low-field benchtop NMR spectroscopy as a potential non-stationary tool for point-of-care urinary metabolite tracking in diabetic conditions

journal contribution
posted on 13.05.2021, 12:31 by Mark Edgar, Benita C Percival, Miles Gibson, Fereshteh Jafari, Martin Grootveld
We describe the advantages and diagnostic/prognostic significance of low-field, near-portable benchtop NMR spectrometers for the multicomponent metabolomics analysis of targeted and untargeted urinary biomarkers (≥15) in type 2 diabetes patients. Implementation of these facilities at ‘point-of-care’ clinical sites may yield valuable advantages for the sequential monitoring of diabetic and prediabetic individuals.

History

School

  • Science

Department

  • Chemistry

Published in

Diabetes Research and Clinical Practice

Volume

171

Publisher

Elsevier BV

Version

P (Proof)

Rights holder

© Elsevier

Publisher statement

This paper was accepted for publication in the journal Diabetes Research and Clinical Practice and the definitive published version is available at https://doi.org/10.1016/j.diabres.2020.108554.

Acceptance date

10/11/2020

Publication date

2020-11-22

Copyright date

2020

DOI

ISSN

0168-8227

Publisher version

Language

en

Depositor

Dr Mark Edgar. Deposit date: 12 May 2021

Article number

108554

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Low-field benchtop NMR spectroscopy as a potential non-stationary tool for point-of-care urinary metabolite tracking in diabetic conditions
Loughborough Publications

Categories

Keywords

Type 2 diabetesPrediabetesNon-stationary benchtop 60 MHz NMR analysisNMR-based metabolomicsBiomarkers

Licence

CC BY-NC-ND 4.0

Exports