Robinson et al 2014 for IR.pdf (292.6 kB)
Low temperature cell pausing: an alternative short-term preservation method for use in cell therapies including stem cell applications
journal contributionposted on 2014-03-06, 15:56 authored by Nathalie J. Robinson, Andy Picken, Karen CoopmanKaren Coopman
Encouraging advances in cell therapies have produced a requirement for an effective short-term cell preservation method, enabling time for quality assurance testing and transport to their clinical destination. Low temperature pausing of cells offers many advantages over cryopreservation, including the ability to store cells at scale, reduced cost and a simplified procedure with increased reliability. This review will focus on the importance of developing a short-term cell preservation platform as well highlighting the major successes of cell pausing and the key challenges which need addressing, to enable application of the process to therapeutically relevant cells.
- Aeronautical, Automotive, Chemical and Materials Engineering
- Chemical Engineering
CitationROBINSON, N.J., PICKEN, A. and COOPMAN, K., 2014. Low temperature cell pausing: an alternative short-term preservation method for use in cell therapies including stem cell applications. Biotechnology Letters, 36 (2), pp. 201 - 209.
- AM (Accepted Manuscript)
NotesThis article was published in the journal, Biotechnology Letters [© Springer] and the definitive version is available at: http://dx.doi.org/10.1007/s10529-013-1349-5