Wadley (2015) Low volume–high intensity interval exercise elicits antioxidant and anti-inflammatory effects in humans.pdf (288.2 kB)
Download file

Low volume–high intensity interval exercise elicits antioxidant and anti-inflammatory effects in humans

Download (288.2 kB)
journal contribution
posted on 01.05.2018, 15:44 by Alex Wadley, Yu-Wen Chen, Gregory Y. Lip, James P. Fisher, Sarah Aldred
The purpose of the present study was to compare acute changes in oxidative stress and inflammation in response to steady state and low volume, high intensity interval exercise (LV-HIIE). Untrained healthy males (n = 10, mean ± s: age 22 ± 3 years; VO2MAX 42.7 ± 5.0 ml · kg−1 · min−1) undertook three exercise bouts: a bout of LV-HIIE (10 × 1 min 90% VO2MAX intervals) and two energy-matched steady-state cycling bouts at a moderate (60% VO2MAX; 27 min, MOD) and high (80% VO2MAX; 20 min, HIGH) intensity on separate days. Markers of oxidative stress, inflammation and physiological stress were assessed before, at the end of exercise and 30 min post-exercise (post+30). At the end of all exercise bouts, significant changes in lipid hydroperoxides (LOOH) and protein carbonyls (PCs) (LOOH (nM): MOD +0.36; HIGH +3.09; LV-HIIE +5.51 and PC (nmol · mg−1 protein): MOD −0.24; HIGH −0.11; LV-HIIE −0.37) were observed. Total antioxidant capacity (TAC) increased post+30, relative to the end of all exercise bouts (TAC (µM): MOD +189; HIGH +135; LV-HIIE +102). Interleukin (IL)-6 and IL-10 increased post+30 in HIGH and LV-HIIE only (P < 0.05). HIGH caused the greatest lymphocytosis, adrenaline and cardiovascular response (P < 0.05). At a reduced energy cost and physiological stress, LV-HIIE elicited similar cytokine and oxidative stress responses to HIGH.

Funding

This work was supported by the University of Birmingham, UK.

History

School

  • Sport, Exercise and Health Sciences

Published in

Journal of Sports Sciences

Volume

34

Issue

1

Pages

1 - 9

Citation

WADLEY, A.J. ... et al, 2016. Low volume–high intensity interval exercise elicits antioxidant and anti-inflammatory effects in humans. Journal of Sports Sciences, 34 (1), pp.1-9.

Publisher

© Taylor & Francis

Version

VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2015

Notes

This paper is closed access.

ISSN

0264-0414

eISSN

1466-447X

Language

en