Monofunctionalized fluorinated bambusurils and their conjugates for anion transport and extraction
journal contribution
posted on 2023-02-17, 09:40 authored by Nicola Alessandro De Simone, Matúš Chvojka, Jana Lapešová, Luis Martínez-Crespo, Petr Slávik, Jan Sokolov, Stephen ButlerStephen Butler, Hennie Valkenier, Vladimír ŠindelářBambusurils are macrocyclic molecules that are known for their high binding affinity and selectivity toward anions. Here, we present the preparation of two bambusurils bearing fluorinated substituents and one carboxylic function. These monofunctionalized bambusurils were conjugated with crown ether and cholesterol units. The resulting conjugates were successfully tested in liquid-liquid extraction of inorganic salts and chloride/bicarbonate transport across lipid bilayers.
Funding
Monofunctionalized bambusurils and their supramolecular properties
Czech Science Foundation
Find out more...RECETOX Research Infrastructure (No. LM2018121)
Transport of phosphorylated compounds across lipid bilayers by supramolecular receptors
European Research Council
Find out more...Czech Infrastructure for Integrative Structural Biology
Ministry of Education Youth and Sports
Find out more...FNRS for Aspirant fellowship funding (40006851)
Luminescent Host Molecules for Multisite Recognition of Polyphosphate Anions
Engineering and Physical Sciences Research Council
Find out more...History
School
- Science
Department
- Chemistry
Published in
The Journal of Organic ChemistryVolume
87Issue
15Pages
9829 - 9838Publisher
American Chemical Society (ACS)Version
- AM (Accepted Manuscript)
Rights holder
© American Chemical SocietyPublisher statement
© 2022 American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in The Journal of Organic Chemistry, after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.joc.2c00870, see ACS Articles on Request https://pubs.acs.org/page/4authors/benefits/index.html#articles-request]Publication date
2022-07-21Copyright date
2022ISSN
0022-3263eISSN
1520-6904Publisher version
Language
- en
