Multiplexed droplet Interface bilayer formation
journal contribution
posted on 2016-12-15, 13:51 authored by Nathan E. Barlow, Guido Bolognesi, Anthony J. Flemming, Nicholas J. Brooks, Laura M.C. Barter, Oscar CesWe present a simple method for the multiplexed formation of droplet interface bilayers (DIBs) using a mechanically operated linear acrylic chamber array. To demonstrate the functionality of the chip design, a lipid membrane permeability assay is performed. We show that multiple, symmetric DIBs can be created and separated using this robust low-cost approach.
Funding
The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under REA grant agreement no 607466. This research was funded by EPSRC grants: EP/J017566/1, EP/L015498/1, EP/ J021199/1 and EP/K503733/1.
History
School
- Aeronautical, Automotive, Chemical and Materials Engineering
Department
- Chemical Engineering
Published in
Lab ChipVolume
16Issue
24Pages
4653 - 4657Citation
BARLOW, N.E. ... et al, 2016. Multiplexed droplet Interface bilayer formation. Lab Chip, 16 (24), pp. 4653 - 4657.Publisher
Royal Society of ChemistryVersion
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/Acceptance date
2016-11-02Publication date
2016-11-10Copyright date
2016Notes
This is an open access article published by the Royal Society of Chemistry and distributed under the terms of the Creative Commons Attribution Licence (CC BY 3.0), https://creativecommons.org/licenses/by/3.0/ISSN
1473-0197eISSN
1473-0189Publisher version
Language
- en
