Multiplexed droplet Interface bilayer formation
journal contributionposted on 15.12.2016, 13:51 authored by Nathan E. Barlow, Guido BolognesiGuido Bolognesi, Anthony J. Flemming, Nicholas J. Brooks, Laura M.C. Barter, Oscar Ces
We present a simple method for the multiplexed formation of droplet interface bilayers (DIBs) using a mechanically operated linear acrylic chamber array. To demonstrate the functionality of the chip design, a lipid membrane permeability assay is performed. We show that multiple, symmetric DIBs can be created and separated using this robust low-cost approach.
The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under REA grant agreement no 607466. This research was funded by EPSRC grants: EP/J017566/1, EP/L015498/1, EP/ J021199/1 and EP/K503733/1.
- Aeronautical, Automotive, Chemical and Materials Engineering
- Chemical Engineering