posted on 2015-07-28, 07:51authored byRay Jones, James P. Bullous, Ching-Man (Carole) Law, Mark ElsegoodMark Elsegood
A range of N-acylpyrrolo[3,4-c]isoxazoles and derived N-5 acyltetramides has been prepared via a nitrile oxide dipolar cycloaddition approach, as analogues of the acyltetramic acid metabolite reutericyclin, of interest for their antibiotic potential against Gram-positive bacteria including hospital-acquired infections of resistant Clostridium difficile.
History
School
Science
Department
Chemistry
Published in
CHEMICAL COMMUNICATIONS
Volume
50
Issue
13
Pages
1588 - 1590 (3)
Citation
JONES, R.C.F. ... et al, 2014. New routes towards reutericyclin analogues. Chemical Communications, 50 (13), pp.1588-1590
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/
Publication date
2014
Notes
This paper was submitted for publication in the journal Chemical Communications. The definitive version can be found at: http://dx.doi.org/10.1039/c3cc47867j