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New solid-state fermentation process for repeated batch production of fibrinolytic enzyme by Fusarium oxysporum

journal contribution
posted on 2017-05-12, 15:46 authored by Tao SunTao Sun, Beihui Liu, Peng Li, Deming Liu, Zuohu Li
novel solid-state fermentation system using rice chaff as carrier/substrate impregnated with mineral solution was developed in order to produce, repeatedly, an industrially useful enzyme. Fusarium oxysporum and a fibrinolytic enzyme was used as the model microorganism and target product, respectively. The dry spores were pneumatically inoculated and incubated for 96 hours, resulting in immobilized F. oxysporum cells on moist substrate. The ability of the immobilized culture to perform a long-term operation was confirmed by repeated batch fermentation. Production of the enzyme continued for 31.5 days and total fibrinolytic enzyme activity reached 154500 IU/litre bulk volume.

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Chemical Engineering

Published in

Process Biochemistry

Volume

33

Issue

4

Pages

419 - 422

Citation

SUN, T. ... et al, 1998. New solid-state fermentation process for repeated batch production of fibrinolytic enzyme by Fusarium oxysporum. Process Biochemistry, 33 (4), pp.419-422

Publisher

© Elsevier

Version

  • NA (Not Applicable or Unknown)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

1998

Notes

This paper is closed access.

ISSN

1359-5113

Language

  • en

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