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Download fileObservations on the modified Wenker synthesis of aziridines and the development of a biphasic system
journal contribution
posted on 2013-03-26, 15:50 authored by Benjamin BuckleyBenjamin Buckley, Anish P. Patel, Upul Wijayantha-Kahagala-GamageA cheap and reliable process for the modified Wenker cyclization to afford
aziridines has been achieved using biphasic conditions for a range of amino alcohol
starting materials. A 100 mmol “one-pot” process has also been devised and
enantiopurity of the starting amino alcohol is retained in the aziridine product.
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