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Observations on the modified Wenker synthesis of aziridines and the development of a biphasic system

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journal contribution
posted on 26.03.2013, 15:50 by Benjamin BuckleyBenjamin Buckley, Anish P. Patel, Upul Wijayantha-Kahagala-Gamage
A cheap and reliable process for the modified Wenker cyclization to afford aziridines has been achieved using biphasic conditions for a range of amino alcohol starting materials. A 100 mmol “one-pot” process has also been devised and enantiopurity of the starting amino alcohol is retained in the aziridine product.

History

School

  • Science

Department

  • Chemistry

Citation

BUCKLEY, B.R., PATEL, A.P. and WIJAYANTHA, K.G.U., 2013. Observations on the modified Wenker synthesis of aziridines and the development of a biphasic system. Journal of Organic Chemistry, 78 (3), pp.1289-1292.

Publisher

© American Chemical Society

Version

AM (Accepted Manuscript)

Publication date

2013

Notes

This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Organic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/jo302615g

ISSN

0022-3263

eISSN

1520-6904

Language

en

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