One-pot synthesis of (R)-convolutamydine A involving in situ chiral organocatalyst formation

Wei, Shengwei; Schmid, Bernard; Macaev, Fliur Z.; Curlat, Serghei N; Malkov, Andrei; Tsogoeva, Svetlana B.

asorg-2014-0002-4.pdf (772.52 kB)

One-pot synthesis of (R)-convolutamydine A involving in situ chiral organocatalyst formation

journal contribution

posted on 23.09.2015, 15:08 by Shengwei Wei, Bernard Schmid, Fliur Z. Macaev, Serghei N Curlat, Andrei MalkovAndrei Malkov, Svetlana B. Tsogoeva

The application of a convenient one-pot synthetic strategy, utilizing an in situ formed organocatalyst, to the enantioselective synthesis of anti-leukaemia agent (R)-convolutamydine A has been demonstrated.

Funding

S.B.T is grateful to the Interdisciplinary Center for Molecular Materials (ICMM), Erlangen Catalysis Resource Center (ECRC) and Deutsche Forschungsgemeinschaft (DFG) for research support. S.B.T. and F.Z.M. acknowledge financial support from the BMBF and AȘM (bilateral BMBF-AȘM project Ref. № MDA 08/010 and № 09.820.05.08 GF).

History

School

Science

Department

Chemistry

Published in

Asymmetric Catalysis

Volume

2

Issue

1

Pages

1 - 6 (6)

Citation

WEI, S. ... et al, 2015. One-pot synthesis of (R)-convolutamydine A involving in situ chiral organocatalyst formation. Asymmetric Catalysis, 2 (1), pp. 1 - 6.

Publisher

De Gruyter Open / © The Authors

Version

VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Unported (CC BY-NC-ND 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-nd/3.0/