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Polymer translocation in an environment of active rods

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journal contribution
posted on 2023-10-17, 08:36 authored by Hamidreza Khalilian, Jalal Sarabadani, Tapio Ala-NissilaTapio Ala-Nissila
We consider the dynamics of a translocation process of a flexible linear polymer through a nanopore into an environment of active rods in the trans side. Using Langevin dynamics simulations, we show that the rods facilitate translocation to the trans side even when there are initially more monomers on the cis than on the trans side. Structural analysis of the translocating polymer reveals that active rods induce a folded structure to the trans-side subchain in the case of successful translocation events. By keeping the initial number of monomers on the cis-side subchain fixed, we map out a state diagram for successful events as a function of the rod number density for a variety of system parameters. This reveals competition between facilitation by the rods at low densities and crowding that hinders translocation at higher densities.

Funding

Academy of Finland through its PolyDyna (No. 307806) and QFT Center of Excellence Program Grants (No. 312298)

History

School

  • Science

Department

  • Mathematical Sciences

Published in

Physical Review Research

Volume

5

Issue

2

Publisher

American Physical Society

Version

  • VoR (Version of Record)

Rights holder

© The Authors

Publisher statement

Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International (https://creativecommons.org/licenses/by/4.0/) license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI.

Acceptance date

2023-04-05

Publication date

2023-05-18

Copyright date

2023

eISSN

2643-1564

Language

  • en

Depositor

Prof Tapio Ala-Nissila. Deposit date: 13 October 2023

Article number

023107

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