Loughborough University
Browse

Post-exercise rehydration: Comparing the efficacy of three commercial oral rehydration solutions

Download (2.23 MB)
journal contribution
posted on 2025-06-05, 13:17 authored by Donald Peden, Mark Funnell, Kirsty Reynolds, Robert W Kenefick, Samuel N Cheuvront, Stephen MearsStephen Mears, Lewis JamesLewis James

Introduction

This study compared the efficacy of three commercial oral rehydration solutions (ORS) for restoring fluid and electrolyte balance, after exercise-induced dehydration.

Method

Healthy, active participants (N = 20; ♀ = 3; age ∼27 y, V˙O2peak ∼52 ml/kg/min) completed three randomised, counterbalanced trials whereby intermittent exercise in the heat (∼36°C, ∼50% humidity) induced ∼2.5% dehydration. Subsequently, participants rehydrated (125% fluid loss in four equal aliquots at 0, 1, 2, 3 h) with a glucose-based (G-ORS), sugar-free (Z-ORS) or amino acid-based sugar-free (AA-ORS) ORS of varying electrolyte composition. Urine output was measured hourly and capillary blood samples collected pre-exercise, 0, 2 and 5 h post-exercise. Sodium, potassium, and chloride concentrations in urine, sweat, and blood were determined.

Results

Net fluid balance peaked at 4 h and was greater in AA-ORS (141 ± 155 ml) and G-ORS (101 ± 195 ml) than Z-ORS (−47 ± 208 ml; P ≤ 0.010). Only AA-ORS achieved positive sodium and chloride balance post-exercise, which were greater for AA-ORS than G-ORS and Z-ORS (P ≤ 0.006), as well as for G-ORS than Z-ORS (P ≤ 0.007) from 1 to 5 h.

Conclusion

When provided in a volume equivalent to 125% of exercise-induced fluid loss, AA-ORS produced comparable/superior fluid balance and superior sodium/chloride balance responses to popular glucose-based and sugar-free ORS.

Funding

Entrinsic Beverage Company LLC, Entrinsic Bioscience, LLC, Norwood, Massachusetts, USA.

History

School

  • Sport, Exercise and Health Sciences

Published in

Frontiers in Sports and Active Living

Volume

5

Publisher

Frontiers Media SA

Version

  • VoR (Version of Record)

Rights holder

©The Author(s)

Publisher statement

This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Acceptance date

2023-04-04

Publication date

2023-04-27

Copyright date

2023

eISSN

2624-9367

Language

  • en

Depositor

Dr Lewis James. Deposit date: 18 March 2025

Article number

1158167

Usage metrics

    Loughborough Publications

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC