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Potential of microneedle systems for COVID-19 vaccination: current trends and challenges

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posted on 2022-05-19, 08:50 authored by Jasmin Hassan, Charlotte Haigh, Tanvir Ahmed, Md Jasim Uddin, Diganta DasDiganta Das

To prevent the coronavirus disease 2019 (COVID-19) pandemic and aid the restoration to pre-pandemic normality, a global mass vaccination is urgently needed. Inducing herd immunity through mass vaccination has proven to be a highly effective strategy for preventing the spread of many infectious diseases, which protect the most vulnerable population groups that are unable to develop immunity, such as people with immunodeficiencies or weakened immune systems due to underlying medical or debilitating conditions. To have a global outreach, the maintenance of the vaccine potency, transportation, needle waste generation becomes a major issue. Moreover, needle phobia and vaccine hesitancy acts as a hurdle for successful mass vaccination. The use of dissolvable microneedles for the COVID-19 vaccination could act as a major paradigm shift in attaining the desired goal to vaccinate billions in the shortest time possible. In addressing these points, we discuss the potential of the use of dissolvable microneedles for COVID-19 vaccination based on the current literature.

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Chemical Engineering

Published in

Pharmaceutics

Volume

14

Issue

5

Publisher

MDPI AG

Version

  • VoR (Version of Record)

Rights holder

© The Authors

Publisher statement

This is an Open Access Article. It is published by MDPI under the Creative Commons Attribution 4.0 International Licence (CC BY). Full details of this licence are available at: https://creativecommons.org/licenses/by/4.0/

Acceptance date

2022-05-09

Publication date

2022-05-16

Copyright date

2022

ISSN

1999-4923

Language

  • en

Depositor

Dr Diganta Das. Deposit date: 9 May 2022

Article number

1066

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