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Prevalence and predictors of age related macular degeneration in the population of Punjab: North Indian age related macular degeneration epidemiology and molecular genetic study (NI-ARMEMS)

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journal contribution
posted on 30.11.2018, 15:56 by Ritu Sharma, Kanchan Mehta, Jasvinder Singh Bhatti, Sarabjit MastanaSarabjit Mastana, Monica Singh, Puneetpal Singh
Background: Age related macular degeneration (AMD) is an ocular disease that is threatening elderly population of Punjab for vision impairment and blindness. Comprehensive understanding of the susceptible factors still remains to be explored in this region. Objective: To examine the risk variables which are independently associated with the risk of AMD along with the investigation of its prevalence in the population of Punjab. Methods: A case-control study by design involved 416 subjects (cases; 219, controls; 197) of age ranging from 45 to 75 years. Various risk factors were investigated for their role in consenting and confirmed AMD subjects along with controls. Results: In the univariate full factorial regression analysis, advancing age (≥66years), being a woman, diastolic blood pressure (DBP) (>80mmHg), cigarette smoking, alcohol drinking, body mass index (BMI) (23-29.9Kgm-2 and ≥30Kgm-2 ), sedentary life style, total cholesterol (>200mg/dl), low density lipoproteins (>100mg/dl), high density lipoproteins (≥40mg/dl), non-vegetarian diet and positive family history were found to be risky determinants. Multivariable stepwise regression analysis revealed age ≥66 years, DBP > 80mmHg, alcohol drinking and smoking as independent predictors for the risk of AMD. Conclusion: Considerable prevalence of dry AMD (20.5%) is evident in the population of Punjab which is mediated independently by age (≥66 years), DBP (>80 mmHg), alcohol drinking and smoking.

History

School

  • Sport, Exercise and Health Sciences

Published in

International journal of health sciences and research

Volume

8

Issue

10

Pages

1 - 8

Citation

SHARMA, R. ... et al., 2018. Prevalence and predictors of age related macular degeneration in the population of Punjab: North Indian age related macular degeneration epidemiology and molecular genetic study (NI-ARMEMS). International journal of health sciences and research, 8(10), pp. 1-8.

Publisher

© International Journal of Health Sciences and Research

Version

VoR (Version of Record)

Acceptance date

07/10/2018

Publication date

2018-10-01

Notes

This paper is open access, users shall have the right to "read, download, copy, distribute, print, search, or link" to the full text.

ISSN

2249-9571

Language

en