2019 - Day et al - Future Sci OA.pdf (1.62 MB)
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Probiotics: current landscape and future horizons

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journal contribution
posted on 08.05.2019, 15:43 by Richard L. Day, Ashton J. Harper, Rachel M. Woods, Owen DaviesOwen Davies, Liam HeaneyLiam Heaney
In recent years there has been a rapid rise in interest for the application of probiotic supplements to act as mediators in health and disease. This appeal is predominantly due to ever-increasing evidence of the interaction of the microbiota and pathophysiological processes of disease within the human host. This narrative review considers the current landscape of the probiotic industry and its research, and discusses current pitfalls in the lack of translation from laboratory science to clinical application. Future considerations into how industry and academia must adapt probiotic research to maximize success are suggested, including more targeted application of probiotic strains dependent on individual capabilities as well as application of multiple advanced analytical technologies to further understand and accelerate microbiome science. Lay abstract: The global market for probiotic supplements is continually expanding. Despite the public perception of benefits provided by probiotics, the evidence to conclusively link probiotic strains to improved characteristics of health or disease is lacking. This is owing, in part, to the lack of large-scale research trials, but also to the insufficient understanding of the interactions occurring within the human system following supplementation. More in-depth research into individual probiotic strains, combined with the application of multiple advanced measurement techniques will provide a future direction for probiotic research and, in turn, aim to provide useful data to translate into routine healthcare practice.

Funding

Yakult Honsha Co., Ltd research grant.

History

School

  • Sport, Exercise and Health Sciences

Published in

Future Science OA

Volume

5

Issue

4

Citation

DAY, R.L. ... et al, 2019. Probiotics: current landscape and future horizons. Future Science OA, 5 (4), FSO391.

Publisher

Future Science © Liam Heaney

Version

VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Acceptance date

25/03/2019

Publication date

2019-05-03

Notes

This work is licensed under the Attribution-NonCommercial-NoDerivatives 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

eISSN

2056-5623

Language

en

Article number

FSO391