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Resonance vibration interventions in the femur: Experimental-numerical modelling approaches

journal contribution
posted on 03.02.2022, 10:15 by Alexandre Presas, David Valentin, Joseph Deering, Marian Kampschulte, Bosco Yu, Kathryn Grandfield, Elisa MeleElisa Mele, Christoph Biehl, Gabriele A Krombach, Christian Heiss, Wolfram A Bosbach
Motive: External vibration excitation might be key to many novel non-surgical interventions for pathologies in the musculoskeletal system and in other parts of the human organism. Lack of understanding about vibration patterns, their controllability, and reproducibility are three limitations of ongoing research. This study establishes a bovine vibration model and animal model replacements for future research. Methods: We used biological samples (n=5) and one polyurethane sample of the bovine femur. Mechanical resonance was measured experimentally and analysed numerically by finite element method. Main results: The experiments obtained 5 distinct mode shapes for the biological sample set, with standard deviation < 7.5%. Finite element analysis of the biological samples can replicate experimental mode shape deflection. The use of polyurethane changes resonance character but results are also good approximations of the biological samples. Conclusions: A model of the bovine femur with consistent resonance behaviour is presented with alternatives (polyurethane and finite element analysis) that can serve in reducing the number of necessary biological samples. Future work will be to adapt results to human anatomy. Of clinical interest will be to influence bone pathologies such as post-surgical non-union, or bone functionality as part of haematopoiesis and endocrine secretion.

Funding

Justus-Liebig fellowship of the Justus-Liebig University President (Giessen, Germany)

Deutsche Forschungsgemeinschaft (DFG) through grant BO 4961/6-1

Serra Hunter programme of the Generalitat de Catalunya

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Materials

Published in

Journal of the Mechanical Behavior of Biomedical Materials

Volume

124

Publisher

Elsevier

Version

AM (Accepted Manuscript)

Rights holder

© Elsevier

Publisher statement

This paper was accepted for publication in the journal Journal of the Mechanical Behavior of Biomedical Materials and the definitive published version is available at https://doi.org/10.1016/j.jmbbm.2021.104850.

Acceptance date

18/09/2021

Publication date

2021-09-20

Copyright date

2021

ISSN

1751-6161

eISSN

1878-0180

Language

en

Depositor

Dr Elisa Mele. Deposit date: 2 February 2022

Article number

104850