The paper describes a combined tribodynamics analysis (dynamics and contact tribology) of cylindrical roller bearings of a heavy duty truck transmission under high applied loads. The dynamic analysis provides the transient variations in contact load. It also determines the vibration spectrum of the bearing as well as that of contact dynamics. It is shown that with sufficient preloading and/or interference fitting a widely spread loaded region results, which reduces bearinginduced vibration. The transient tribological analysis, including thermal analysis with a novel and realistic lubricant inlet boundary condition demonstrates that non-Newtonian mixed elastohydrodynamic regime of lubrication is prevalent, but with reduced friction compared with unrealistic dry Coulombic friction, which is often assumed in literature.