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Seeing the unseen: Could Eulerian video magnification aid clinician detection of subclinical Parkinson’s tremor?

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journal contribution
posted on 17.09.2020, 14:46 by Stefan Williams, Hui FangHui Fang, Samuel Relton, Christopher Graham, Jane Alty
Introduction
Eulerian magnification amplifies very small movements in video, revealing otherwise invisible motion. This raises the possibility that it could enable clinician visualisation of subclinical tremor using a standard camera. We tested whether Eulerian magnification of apparently atremulous hands reveals a Parkinsonian tremor more frequently in Parkinson’s than in controls.

Method
We applied Eulerian magnification to smartphone video of 48 hands that appeared atremulous during recording (22 hands from 11 control participants, 26 hands from 17 idiopathic Parkinson’s participants). Videos were rated for Parkinsonian tremor appearance (yes/no) before and after Eulerian magnification by three movement disorder specialist neurologists.

Results
The proportion of hands correctly classified as Parkinsonian or not by clinicians was significantly higher after Eulerian magnification (OR = 2.67; CI = [1.39, 5.17]; p < 0.003). Parkinsonian-appearance tremors were seen after magnification in a number of control hands, but the proportion was greater in the Parkinson’s hands.

Conclusion
Eulerian magnification slightly improves clinician ability to identify apparently atremulous hands as Parkinsonian. This suggests that some of the apparent tremor revealed may be subclinical Parkinson’s (pathological) tremor, and Eulerian magnification may represent a first step towards contactless visualisation of such tremor. However, the technique also reveals apparent tremor in control hands. Therefore, our method needs additional elaboration and would not be of direct clinical use in its current iteration.

History

School

  • Science

Department

  • Computer Science

Published in

Journal of Clinical Neuroscience

Volume

81

Pages

101 - 104

Publisher

Elsevier

Version

AM (Accepted Manuscript)

Rights holder

© Elsevier Ltd

Publisher statement

This paper was accepted for publication in the journal Journal of Clinical Neuroscience and the definitive published version is available at https://doi.org/10.1016/j.jocn.2020.09.046.

Acceptance date

15/09/2020

Publication date

2020-10-02

Copyright date

2020

ISSN

0967-5868

Language

en

Depositor

Dr Hui Fang Deposit date: 15 September 2020